UBE2K 抗体
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北京 101111
Quick Overview for UBE2K 抗体 (ABIN7120554)
抗原
See all UBE2K 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- UBE2K antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- ubiquitin-conjugating enzyme E2K
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亚型
- IgG
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anti-Ubiquitin-Conjugating Enzyme E2K (UBE2K) (AA 109-139) antibody
UBE2K 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB4144 unconjugated
anti-Ubiquitin-Conjugating Enzyme E2K (UBE2K) (AA 1-100) antibodyUBE2K 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2K (UBE2K) (AA 2-200) antibodyUBE2K 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2K (UBE2K) (C-Term) antibodyVerified UBE2K 适用: 人 ELISA, WB, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2K (UBE2K) (C-Term) antibodyUBE2K 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2K (UBE2K) (C-Term) antibodyUBE2K 适用: 人, 小鼠, 大鼠, 斑马鱼, 犬, Cow, 山羊, 马, 兔, 豚鼠, Pig, 猴, Hamster, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2K (UBE2K) (AA 1-40) antibodyUBE2K 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1D10 unconjugated
anti-Ubiquitin-Conjugating Enzyme E2K (UBE2K) (AA 51-150) antibodyUBE2K 适用: 大鼠 ELISA, WB, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2K (UBE2K) (AA 108-157) antibodyUBE2K 适用: 人, 小鼠, 大鼠, 斑马鱼, 犬, Cow, 山羊, 马, 兔, 豚鼠, 小鸡, 非洲爪蟾, Pig, 猴, Hamster, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2K (UBE2K) (N-Term) antibodyUBE2K 适用: 人, 小鼠, 大鼠, 斑马鱼, 犬, Cow, 山羊, 马, 兔, 豚鼠, 小鸡, 非洲爪蟾, Pig, 猴, Hamster WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))
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别名
- UBE2K
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背景
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Synonyms: Ubiquitin-conjugating enzyme E2 K|E2 ubiquitin-conjugating enzyme K|Huntingtin-interacting protein 2 (HIP-2)|Ubiquitin carrier protein|Ubiquitin-conjugating enzyme E2-25 kDa (Ubiquitin-conjugating enzyme E2(25K), Ubiquitin-conjugating enzyme E2-25K)|Ubiquitin-protein ligase|UBE2K|HIP2|LIG
Background: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, in the presence or in the absence of BRCA1-BARD1 E3 ubiquitin-protein ligase complex, catalyzes the synthesis of 'Lys-48'-linked polyubiquitin chains. Does not transfer ubiquitin directly to but elongates monoubiquitinated substrate protein. Mediates the selective degradation of short-lived and abnormal proteins, such as the endoplasmic reticulum-associated degradation(ERAD) of misfolded lumenal proteins. Ubiquitinates huntingtin. May mediate foam cell formation by the suppression of apoptosis of lipid-bearing macrophages through ubiquitination and subsequence degradation of p53/TP53. Proposed to be involved in ubiquitination and proteolytic processing of NF-kappa-B, in vitro supports ubiquitination of NFKB1. In case of infection by cytomegaloviruses may be involved in the US11-dependent degradation of MHC class I heavy chains following their export from the ER to the cytosol. In case of viral infections may be involved in the HPV E7 protein-dependent degradation of RB1.
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分子量
- 25 kDa
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基因ID
- 3093
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UniProt
- P61086
抗原
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