USP9X 抗体
Quick Overview for USP9X 抗体 (ABIN7120533)
抗原
See all USP9X 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- USP9X antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- ubiquitin specific peptidase 9, X-linked
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亚型
- IgG
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应用备注
- WB: 1:500-1:5000, IF: 1:10-1:100, IHC: 1:20-1:200, IP: 1:200-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- USP9X (Ubiquitin Specific Peptidase 9, X-Linked (USP9X))
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别名
- USP9X
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背景
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Synonyms: Probable ubiquitin carboxyl-terminal hydrolase FAF-X|Deubiquitinating enzyme FAF-X|Fat facets in mammals (hFAM)|Fat facets protein-related, X-linked|Ubiquitin thioesterase FAF-X|Ubiquitin-specific protease 9, X chromosome|Ubiquitin-specific-processing protease FAF-X|USP9X|DFFRX|FAM|USP9
Background: Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Regulates chromosome alignment and segregation in mitosis by regulating the localization of BIRC5/survivin to mitotic centromeres. Specifically hydrolyzes both 'Lys-29'-and 'Lys-33'-linked polyubiquitins chains. Specifically deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Involved in axonal growth and neuronal cell migration.
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分子量
- 260-290 kDa
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基因ID
- 8239
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UniProt
- Q93008
抗原
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