USP7 抗体
Quick Overview for USP7 抗体 (ABIN7120532)
抗原
See all USP7 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- USP7 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- ubiquitin specific peptidase 7
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亚型
- IgG
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应用备注
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- USP7 (Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7))
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别名
- USP7
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背景
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Synonyms: Ubiquitin carboxyl-terminal hydrolase 7|Deubiquitinating enzyme 7|Herpesvirus-associated ubiquitin-specific protease|Ubiquitin thioesterase 7|Ubiquitin-specific-processing protease 7|USP7|HAUSP
Background: The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder.
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分子量
- 130 kDa
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基因ID
- 7874
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UniProt
- Q93009
抗原
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