Synonyms:Deubiquitinating enzyme 48, DKFZp762M1713, RAP1GA1, Ubiquitin thiolesterase 48, USP31, USP48 Background:Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. May be involved in the regulation of NF-kappa-B activation by TNF receptor superfamily via its interactions with RELA and TRAF2. May also play a regulatory role at postsynaptic sites.