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USP20 抗体

USP20 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7120505
发货至: 中国
  • 抗原 See all USP20 抗体
    USP20 (Ubiquitin Specific Peptidase 20 (USP20))
    适用
    • 41
    • 11
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 37
    • 4
    • 1
    克隆类型
    • 41
    • 1
    多克隆
    标记
    • 21
    • 5
    • 4
    • 4
    • 4
    • 4
    This USP20 antibody is un-conjugated
    应用范围
    • 29
    • 25
    • 16
    • 4
    • 3
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    ubiquitin specific peptidase 20
    亚型
    IgG
    Top Product
    Discover our top product USP20 Primary Antibody
  • 应用备注
    WB: 1:200-1:2000, IHC: 1:20-1:200,IP: 1:200-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    USP20 (Ubiquitin Specific Peptidase 20 (USP20))
    别名
    USP20 (USP20 产品)
    别名
    USP20 antibody, vdu2 antibody, lsfr3a antibody, LSFR3A antibody, VDU2 antibody, hVDU2 antibody, 1700055M05Rik antibody, AI467231 antibody, Vdu2 antibody, im:7151955 antibody, zgc:63661 antibody, universal stress protein antibody, ubiquitin specific peptidase 20 antibody, ubiquitin specific peptidase 20 L homeolog antibody, RR_RS15875 antibody, USP20 antibody, usp20 antibody, Usp20 antibody, usp20.L antibody
    背景
    Synonyms:Deubiquitinating enzyme 20, hVDU2, KIAA1003, LSFR3A, Ubiquitin thiolesterase 20, USP20, VDU2 Background:Deubiquitinating enzyme involved in beta-2 adrenergic receptor(ADRB2) recycling. Acts as a regulator of G-protein coupled receptor(GPCR) signaling by mediating the deubiquitination beta-2 adrenergic receptor(ADRB2). Plays a central role in ADRB2 recycling and resensitization after prolonged agonist stimulation by constitutively binding ADRB2, mediating deubiquitination of ADRB2 and inhibiting lysosomal trafficking of ADRB2. Upon dissociation, it is probably transferred to the translocated beta-arrestins, possibly leading to beta-arrestins deubiquitination and disengagement from ADRB2. This suggests the existence of a dynamic exchange between the ADRB2 and beta-arrestins. Deubiquitinates DIO2, thereby regulating thyroid hormone regulation. Deubiquitinates HIF1A, leading to stabilize HIF1A and enhance HIF1A-mediated activity. Mediates deubiquitination of both 'Lys-48'-and 'Lys-63'-linked polyubiquitin chains.
    分子量
    110 kDa
    基因ID
    10868
    UniProt
    Q9Y2K6
    途径
    Regulation of G-Protein Coupled Receptor Protein Signaling
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