USP20 抗体
Quick Overview for USP20 抗体 (ABIN7120505)
抗原
See all USP20 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- USP20 antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- ubiquitin specific peptidase 20
-
亚型
- IgG
-
-
anti-Ubiquitin Specific Peptidase 20 (USP20) (Internal Region) antibody
USP20 适用: 人, 犬, 兔, 马, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (Internal Region) antibodyUSP20 适用: 人, 犬, 兔, 马, 小鸡, Cow, Pig, 猴, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (Internal Region) antibodyUSP20 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (AA 252-349) antibodyUSP20 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (C-Term) antibodyVerified USP20 适用: 人 ELISA, WB, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (AA 1-913) antibodyUSP20 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (AA 252-349) antibodyUSP20 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1A6 unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (AA 1-913) antibodyUSP20 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (AA 361-410) antibodyUSP20 适用: 人, 大鼠, 兔, 小鸡, 猴, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (AA 814-844), (C-Term) antibodyUSP20 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB4351 unconjugated
-
-
应用备注
- WB: 1:200-1:2000, IHC: 1:20-1:200,IP: 1:200-1:2000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- USP20 (Ubiquitin Specific Peptidase 20 (USP20))
-
别名
- USP20
-
背景
-
Synonyms: Ubiquitin carboxyl-terminal hydrolase 20|Deubiquitinating enzyme 20|Ubiquitin thioesterase 20|Ubiquitin-specific-processing protease 20|VHL-interacting deubiquitinating enzyme 2 (hVDU2)|USP20|KIAA1003|LSFR3A|VDU2
Background: Deubiquitinating enzyme involved in beta-2 adrenergic receptor(ADRB2) recycling. Acts as a regulator of G-protein coupled receptor(GPCR) signaling by mediating the deubiquitination beta-2 adrenergic receptor(ADRB2). Plays a central role in ADRB2 recycling and resensitization after prolonged agonist stimulation by constitutively binding ADRB2, mediating deubiquitination of ADRB2 and inhibiting lysosomal trafficking of ADRB2. Upon dissociation, it is probably transferred to the translocated beta-arrestins, possibly leading to beta-arrestins deubiquitination and disengagement from ADRB2. This suggests the existence of a dynamic exchange between the ADRB2 and beta-arrestins. Deubiquitinates DIO2, thereby regulating thyroid hormone regulation. Deubiquitinates HIF1A, leading to stabilize HIF1A and enhance HIF1A-mediated activity. Mediates deubiquitination of both 'Lys-48'-and 'Lys-63'-linked polyubiquitin chains.
-
分子量
- 110 kDa
-
基因ID
- 10868
-
UniProt
- Q9Y2K6
-
途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
-
