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USP16 抗体

This anti-USP16 antibody is a 兔 多克隆 antibody detecting USP16 in WB, ELISA, IHC 和 IP. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7120500
发货至: 中国

Quick Overview for USP16 抗体 (ABIN7120500)

抗原

See all USP16 抗体
USP16 (Ubiquitin Specific Peptidase 16 (USP16))

适用

  • 49
  • 11
  • 11
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 45
  • 3
  • 1

克隆类型

  • 48
  • 1
多克隆

标记

  • 26
  • 5
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This USP16 antibody is un-conjugated

应用范围

  • 38
  • 24
  • 11
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    ubiquitin specific peptidase 16

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:5000, IP: 1:500-1:5000, IHC: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    USP16 (Ubiquitin Specific Peptidase 16 (USP16))

    别名

    USP16

    背景

    Synonyms:Deubiquitinating enzyme 16, Ubiquitin thiolesterase 16, UBP M, USP16 Background:Specifically deubiquitinates 'Lys-120' of histone H2A(H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3(H3S10ph), and is required for chromosome segregation when cells enter into mitosis. In resting B-and T-lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B.

    分子量

    94 kDa

    基因ID

    10600

    UniProt

    Q9Y5T5
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