USP14 抗体
Quick Overview for USP14 抗体 (ABIN7120498)
抗原
See all USP14 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- USP14 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- ubiquitin specific peptidase 14(tRNA-guanine transglycosylase)
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亚型
- IgG
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应用备注
- WB: 1:500-1:5000, IP: 1:500-1:5000, IF: 1:10-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- USP14 (Ubiquitin Specific Peptidase 14 (USP14))
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别名
- USP14
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背景
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Synonyms: Ubiquitin carboxyl-terminal hydrolase 14|Deubiquitinating enzyme 14|Ubiquitin thioesterase 14|Ubiquitin-specific-processing protease 14|USP14|TGT
Background: Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation(ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions(NMJs).
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分子量
- 52-60 kDa
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基因ID
- 9097
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UniProt
- P54578
抗原
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