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USP14 抗体

This anti-USP14 antibody is a 兔 多克隆 antibody detecting USP14 in WB, ELISA, IF 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7120498
发货至: 中国

Quick Overview for USP14 抗体 (ABIN7120498)

抗原

See all USP14 抗体
USP14 (Ubiquitin Specific Peptidase 14 (USP14))

适用

  • 64
  • 8
  • 7
  • 4
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 53
  • 10

克隆类型

  • 45
  • 19
多克隆

标记

  • 36
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This USP14 antibody is un-conjugated

应用范围

  • 46
  • 27
  • 17
  • 10
  • 8
  • 6
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    ubiquitin specific peptidase 14(tRNA-guanine transglycosylase)

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:5000, IP: 1:500-1:5000, IF: 1:10-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    USP14 (Ubiquitin Specific Peptidase 14 (USP14))

    别名

    USP14

    背景

    Synonyms:Deubiquitinating enzyme 14, TGT, Ubiquitin thiolesterase 14, USP14 Background:Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation(ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions(NMJs).

    分子量

    52-60 kDa

    基因ID

    9097

    UniProt

    P54578
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