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USP11 抗体

This anti-USP11 antibody is a 兔 多克隆 antibody detecting USP11 in WB, ELISA, IHC, IP 和 IF. Suitable for 人.
产品编号 ABIN7120493
发货至: 中国

Quick Overview for USP11 抗体 (ABIN7120493)

抗原

See all USP11 抗体
USP11 (Ubiquitin Specific Peptidase 11 (USP11))

适用

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宿主

  • 37
  • 7
  • 1

克隆类型

  • 30
  • 15
多克隆

标记

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This USP11 antibody is un-conjugated

应用范围

  • 31
  • 16
  • 11
  • 4
  • 4
  • 3
  • 3
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  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    ubiquitin specific peptidase 11

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:5000, IHC: 1:20-1:200, IP: 1:1000-1:10000, IF: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    USP11 (Ubiquitin Specific Peptidase 11 (USP11))

    别名

    USP11

    背景

    Synonyms:Deubiquitinating enzyme 11, Ubiquitin thiolesterase 11, UHX1, USP11 Background:Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains(PubMed:12084015, PubMed:15314155, PubMed:17897950, PubMed:19874889, PubMed:20233726, PubMed:24724799). Inhibits the degradation of target proteins by the proteasome(PubMed:12084015). Cleaves preferentially 'Lys-6' and 'Lys-63'-linked ubiquitin chains. Has lower activity with 'Lys-11' and 'Lys-33'-linked ubiquitin chains, and extremely low activity with 'Lys-27', 'Lys-29' and 'Lys-48'-linked ubiquitin chains(in vitro)(PubMed:24724799). Plays a role in the regulation of pathways leading to NF-kappa-B activation(PubMed:17897950, PubMed:19874889). Plays a role in the regulation of DNA repair after double-stranded DNA breaks(PubMed:15314155, PubMed:20233726).

    分子量

    110 kDa

    基因ID

    8237

    UniProt

    P51784
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