USP1 抗体 (AA 430-785)
Quick Overview for USP1 抗体 (AA 430-785) (ABIN7120490)
抗原
See all USP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 430-785
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原理
- USP1 antibody
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纯化方法
- Protein A+G purification
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 430-785aa
Immunogen: ubiquitin specific peptidase 1
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亚型
- IgG1
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应用备注
- WB: 1:1000-1:10000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- USP1 (Ubiquitin Specific Peptidase 1 (USP1))
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别名
- USP1
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背景
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Synonyms: Ubiquitin carboxyl-terminal hydrolase 1|Deubiquitinating enzyme 1 (hUBP)|Ubiquitin thioesterase 1|Ubiquitin-specific-processing protease 1|Ubiquitin carboxyl-terminal hydrolase 1, N-terminal fragment|USP1
Background: Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2(PubMed:15694335). Also involved in PCNA-mediated translesion synthesis(TLS) by deubiquitinating monoubiquitinated PCNA(PubMed:16531995). Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity(PubMed:18082604, PubMed:26388029).
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分子量
- 90 kDa
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基因ID
- 7398
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UniProt
- O94782
抗原
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