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USP1 抗体 (AA 430-785)

This anti-USP1 antibody is a 小鼠 单克隆 antibody detecting USP1 in WB, ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7120490
发货至: 中国

Quick Overview for USP1 抗体 (AA 430-785) (ABIN7120490)

抗原

See all USP1 抗体
USP1 (Ubiquitin Specific Peptidase 1 (USP1))

适用

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  • 1

宿主

  • 64
  • 2
小鼠

克隆类型

  • 66
单克隆

标记

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  • 1
  • 1
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  • 1
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This USP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

克隆位点

8F7
  • 抗原表位

    • 15
    • 8
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    • 6
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    • 1
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    AA 430-785

    原理

    USP1 antibody

    纯化方法

    Protein A+G purification

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Immunogen sequence: 430-785aa

    Immunogen: ubiquitin specific peptidase 1

    亚型

    IgG1
  • 应用备注

    WB: 1:1000-1:10000, IHC: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    USP1 (Ubiquitin Specific Peptidase 1 (USP1))

    别名

    USP1

    背景

    Synonyms: Ubiquitin carboxyl-terminal hydrolase 1|Deubiquitinating enzyme 1 (hUBP)|Ubiquitin thioesterase 1|Ubiquitin-specific-processing protease 1|Ubiquitin carboxyl-terminal hydrolase 1, N-terminal fragment|USP1

    Background: Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2(PubMed:15694335). Also involved in PCNA-mediated translesion synthesis(TLS) by deubiquitinating monoubiquitinated PCNA(PubMed:16531995). Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity(PubMed:18082604, PubMed:26388029).

    分子量

    90 kDa

    基因ID

    7398

    UniProt

    O94782
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