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UBR2 抗体

UBR2 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7120484
发货至: 中国
  • 抗原 See all UBR2 抗体
    UBR2 (Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))
    适用
    • 35
    • 22
    • 18
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    • 2
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    人, 小鼠
    宿主
    • 30
    • 4
    • 1
    克隆类型
    • 32
    • 3
    多克隆
    标记
    • 17
    • 3
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    • 1
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    This UBR2 antibody is un-conjugated
    应用范围
    • 28
    • 13
    • 13
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    ubiquitin protein ligase E3 component n-recognin 2
    亚型
    IgG
    Top Product
    Discover our top product UBR2 Primary Antibody
  • 应用备注
    WB: 1:200-1:2000, IF:1:10-1:100, IHC: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    UBR2 (Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))
    别名
    UBR2 (UBR2 产品)
    别名
    ba49a4.1 antibody, si:ch211-239i4.2 antibody, C6orf133 antibody, RP3-392M17.3 antibody, bA49A4.1 antibody, dJ242G1.1 antibody, dJ392M17.3 antibody, 9930021A08Rik antibody, AI462103 antibody, AW540746 antibody, E130209G04Rik antibody, mKIAA0349 antibody, ubiquitin protein ligase E3 component n-recognin 2 antibody, ubiquitin protein ligase E3 component n-recognin 2 S homeolog antibody, UBR2 antibody, ubr2 antibody, ubr2.S antibody, Ubr2 antibody
    背景
    Synonyms:BA49A4.1, C6orf133, dJ242G1.1, dJ392M17.3, DKFZp686C08114, KIAA0349, N recognin 2, RP3 392M17.3, UBR2 Background:E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Plays a critical role in chromatin inactivation and chromosome-wide transcriptional silencing during meiosis via ubiquitination of histone H2A. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth.
    分子量
    66 kDa
    基因ID
    23304
    UniProt
    Q8IWV8
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