UBR2 抗体
Our Local Distributor
北京 101111
Quick Overview for UBR2 抗体 (ABIN7120484)
抗原
See all UBR2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- UBR2 antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- ubiquitin protein ligase E3 component n-recognin 2
-
亚型
- IgG
-
-
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (AA 1-100) antibody
UBR2 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 4G4 unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (C-Term) antibodyUBR2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (AA 101-439) antibodyUBR2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) antibodyUBR2 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (Internal Region) antibodyVerified UBR2 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (AA 1-100) antibodyUBR2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (AA 1-439) antibodyUBR2 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (C-Term) antibodyUBR2 适用: 人, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (C-Term) antibodyUBR2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (C-Term) antibodyUBR2 适用: 人, 小鼠, 大鼠, 马, Cow, 犬, 兔, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:200-1:2000, IF:1:10-1:100, IHC: 1:20-1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- UBR2 (Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))
-
别名
- UBR2
-
背景
-
Synonyms: E3 ubiquitin-protein ligase UBR2|N-recognin-2|RING-type E3 ubiquitin transferase UBR2|Ubiquitin-protein ligase E3-alpha-2|Ubiquitin-protein ligase E3-alpha-II|UBR2|C6orf133|KIAA0349
Background: E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Plays a critical role in chromatin inactivation and chromosome-wide transcriptional silencing during meiosis via ubiquitination of histone H2A. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth.
-
分子量
- 66 kDa
-
基因ID
- 23304
-
UniProt
- Q8IWV8
抗原
-
