TNFAIP1 抗体
Quick Overview for TNFAIP1 抗体 (ABIN7120411)
抗原
See all TNFAIP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- TNFAIP1 antibody
-
纯化方法
- Protein A+G purification
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- tumor necrosis factor, alpha-induced protein 1(endothelial)
-
亚型
- IgG1
-
-
-
-
应用备注
- WB: 1:1000-1:6000, IHC: 1:50-1:600
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- TNFAIP1 (Tumor Necrosis Factor, alpha-Induced Protein 1 (Endothelial) (TNFAIP1))
-
别名
- TNFAIP1
-
背景
-
Synonyms: BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (hBACURD2)|BTB/POZ domain-containing protein TNFAIP1|Protein B12|Tumor necrosis factor, alpha-induced protein 1, endothelial|TNFAIP1|BACURD2|EDP1
Background: Substrate-specific adapter of a BCR(BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity.
-
分子量
- 36 kDa
-
基因ID
- 7126
-
UniProt
- Q13829
抗原
-