TRIM6 抗体
Quick Overview for TRIM6 抗体 (ABIN7120296)
抗原
See all TRIM6 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- TRIM6 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 229-422
Immunogen: tripartite motif-containing 6
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- TRIM6 (Tripartite Motif Containing 6 (TRIM6))
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别名
- TRIM6
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背景
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Synonyms: Tripartite motif-containing protein 6|RING finger protein 89|RING-type E3 ubiquitin transferase TRIM6|TRIM6|RNF89
Background: E3 ubiquitin-protein ligase which ubiquitinates MYC and inhibits its transcription activation activity, maintaining the pluripotency of embryonic stem cells(By similarity). Involved in the synthesis of unanchored K48-linked polyubiquitin chains which interact with and activate the serine/threonine kinase IKBKE, leading to phosphorylation of STAT1 and stimulation of an antiviral response(PubMed:24882218).
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分子量
- 56 kDa
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基因ID
- 117854
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UniProt
- Q9C030
抗原
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