TRIM37 抗体
Quick Overview for TRIM37 抗体 (ABIN7120286)
抗原
See all TRIM37 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- TRIM37 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- tripartite motif-containing 37
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亚型
- IgG
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应用备注
- WB: 1:200-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- TRIM37 (Tripartite Motif Containing 37 (TRIM37))
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别名
- TRIM37
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背景
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Synonyms: E3 ubiquitin-protein ligase TRIM37|Mulibrey nanism protein|RING-type E3 ubiquitin transferase TRIM37|Tripartite motif-containing protein 37|TRIM37|KIAA0898|MUL|POB1
Background: E3 ubiquitin-protein ligase required to prevent centriole reduplication(PubMed:15885686, PubMed:23769972). Probably acts by ubiquitinating positive regulators of centriole reduplication(PubMed:23769972). Mediates monoubiquitination of 'Lys-119' of histone H2A(H2AK119Ub), a specific tag for epigenetic transcriptional repression: associates with some Polycomb group(PcG) multiprotein PRC2-like complex and mediates repression of target genes(PubMed:25470042). Has anti-HIV activity(PubMed:24317724).
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分子量
- 100 kDa, 130 kDa
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基因ID
- 4591
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UniProt
- O94972
抗原
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