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TRIM25 抗体

This anti-TRIM25 antibody is a 兔 多克隆 antibody detecting TRIM25 in WB, ELISA, IF 和 IP. Suitable for 人 和 小鼠.
产品编号 ABIN7120280
发货至: 中国

Quick Overview for TRIM25 抗体 (ABIN7120280)

抗原

See all TRIM25 抗体
TRIM25 (Tripartite Motif Containing 25 (TRIM25))

适用

  • 90
  • 10
  • 7
  • 5
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
人, 小鼠

宿主

  • 85
  • 6

克隆类型

  • 82
  • 9
多克隆

标记

  • 48
  • 5
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TRIM25 antibody is un-conjugated

应用范围

  • 80
  • 32
  • 27
  • 27
  • 20
  • 14
  • 13
  • 10
  • 9
  • 7
  • 5
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    tripartite motif-containing 25

    亚型

    IgG
  • 应用备注

    WB: 1:200-1:2000, IP: 1:200-1:2000, IF: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    TRIM25 (Tripartite Motif Containing 25 (TRIM25))

    别名

    TRIM25

    背景

    Synonyms:EFP,RING finger protein 147, RNF147, TRIM25, tripartite motif containing 25, Z147, Zinc finger protein 147, ZNF147 Background:Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection. Promotes ISGylation of 14-3-3 sigma(SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway. Mediates estrogen action in various target organs. Mediates the ubiquitination and subsequent proteasomal degradation of ZFHX3(PubMed:22452784).

    分子量

    71 kDa

    基因ID

    7706

    UniProt

    Q14258
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