TRIM25 抗体
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北京 101111
Quick Overview for TRIM25 抗体 (ABIN7120280)
抗原
See all TRIM25 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- TRIM25 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- tripartite motif-containing 25
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亚型
- IgG
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anti-Tripartite Motif Containing 25 (TRIM25) (AA 211-360) antibody
TRIM25 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 5B5B12 unconjugated
anti-Tripartite Motif Containing 25 (TRIM25) (AA 100-400) antibodyTRIM25 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 25 (TRIM25) (AA 211-310) antibodyTRIM25 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 5C3 unconjugated
anti-Tripartite Motif Containing 25 (TRIM25) (AA 81-272) antibodyTRIM25 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 25 (TRIM25) (AA 1-630) antibodyTRIM25 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 25 (TRIM25) (AA 1-630) antibodyTRIM25 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Tripartite Motif Containing 25 (TRIM25) antibodyTRIM25 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 25 (TRIM25) (C-Term) antibodyTRIM25 适用: 人, 小鼠 WB, ELISA, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 25 (TRIM25) (AA 243-491) antibodyTRIM25 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 25 (TRIM25) (AA 531-630) antibodyTRIM25 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:200-1:2000, IP: 1:200-1:2000, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- TRIM25 (Tripartite Motif Containing 25 (TRIM25))
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别名
- TRIM25
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背景
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Synonyms: E3 ubiquitin/ISG15 ligase TRIM25|Estrogen-responsive finger protein|RING finger protein 147|RING-type E3 ubiquitin transferase|RING-type E3 ubiquitin transferase TRIM25|Tripartite motif-containing protein 25|Ubiquitin/ISG15-conjugating enzyme TRIM25|Zinc finger protein 147|TRIM25|EFP|RNF147|ZNF147
Background: Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection. Promotes ISGylation of 14-3-3 sigma(SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway. Mediates estrogen action in various target organs. Mediates the ubiquitination and subsequent proteasomal degradation of ZFHX3(PubMed:22452784).
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分子量
- 71 kDa
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基因ID
- 7706
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UniProt
- Q14258
抗原
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