TRIM24 抗体
Quick Overview for TRIM24 抗体 (ABIN7120279)
抗原
See all TRIM24 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- TRIM24 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- tripartite motif-containing 24
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亚型
- IgG
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anti-Tripartite Motif Containing 24 (TRIM24) (AA 432-569) antibody
TRIM24 适用: 人 WB, ELISA, IF, IP, IHC (p) 宿主: 小鼠 Monoclonal 2F2 unconjugated
anti-Tripartite Motif Containing 24 (TRIM24) (AA 789-843), (C-Term) antibodyTRIM24 适用: 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB51160 unconjugated
anti-Tripartite Motif Containing 24 (TRIM24) (C-Term) antibodyTRIM24 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 24 (TRIM24) (C-Term) antibodyTRIM24 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 24 (TRIM24) antibodyTRIM24 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 24 (TRIM24) (C-Term) antibodyTRIM24 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 24 (TRIM24) (AA 1-1050) antibodyTRIM24 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 24 (TRIM24) (AA 503-552) antibodyTRIM24 适用: 人, 大鼠, Cow, 豚鼠, 马, 兔, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 24 (TRIM24) (C-Term) antibodyTRIM24 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, Pig, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 24 (TRIM24) (AA 600-820) antibodyTRIM24 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:5000, IP: 1:200-1:2000, IHC: 1:50-1:200, IF: 1:50-1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- TRIM24 (Tripartite Motif Containing 24 (TRIM24))
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别名
- TRIM24
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背景
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Synonyms: Transcription intermediary factor 1-alpha (TIF1-alpha)|E3 ubiquitin-protein ligase TRIM24|RING finger protein 82|RING-type E3 ubiquitin transferase TIF1-alpha|Tripartite motif-containing protein 24|TRIM24|RNF82|TIF1|TIF1A
Background: Transcriptional coactivator that interacts with numerous nuclear receptors and coactivators and modulates the transcription of target genes. Interacts with chromatin depending on histone H3 modifications, having the highest affinity for histone H3 that is both unmodified at 'Lys-4'(H3K4me0) and acetylated at 'Lys-23'(H3K23ac). Has E3 protein-ubiquitin ligase activity. Promotes ubiquitination and proteasomal degradation of p53/TP53. Plays a role in the regulation of cell proliferation and apoptosis, at least in part via its effects on p53/TP53 levels. Up-regulates ligand-dependent transcription activation by AR, GCR/NR3C1, thyroid hormone receptor(TR) and ESR1. Modulates transcription activation by retinoic acid(RA) receptors, including RARA. Plays a role in regulating retinoic acid-dependent proliferation of hepatocytes(By similarity).
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分子量
- 117 kDa
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基因ID
- 8805
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UniProt
- O15164
抗原
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