TRIM11 抗体
Quick Overview for TRIM11 抗体 (ABIN7120272)
抗原
See all TRIM11 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- tripartite motif-containing 11
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亚型
- IgG
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anti-Tripartite Motif Containing 11 (TRIM11) (AA 267-468) antibody
TRIM11 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 11 (TRIM11) (AA 383-432) antibodyTRIM11 适用: 人, 小鼠, 大鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 11 (TRIM11) (AA 249-263) antibodyVerified TRIM11 适用: 人 ELISA, WB, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Tripartite Motif Containing 11 (TRIM11) (C-Term) antibodyVerified TRIM11 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Tripartite Motif Containing 11 (TRIM11) (AA 267-468) antibodyTRIM11 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 11 (TRIM11) (AA 300-329), (C-Term) antibodyTRIM11 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB33239 unconjugated
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应用备注
- WB: 1:200-1:1000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- TRIM11 (Tripartite Motif Containing 11 (TRIM11))
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别名
- TRIM11
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背景
- Synonyms:BIA1, Protein BIA1, RING finger protein 92, RNF92, TRIM11, tripartite motif containing 11 Background:E3 ubiquitin-protein ligase that promotes the degradation of insoluble ubiquitinated proteins, including insoluble PAX6, poly-Gln repeat expanded HTT and poly-Ala repeat expanded ARX. Mediates PAX6 ubiquitination leading to proteasomal degradation, thereby modulating cortical neurogenesis. May also inhibit PAX6 transcriptional activity, possibly in part by preventing the binding of PAX6 to its consensus sequences. May contribute to the regulation of the intracellular level of HN(humanin) or HN-containing proteins through the proteasomal degradation pathway. Mediates MED15 ubiquitination leading to proteasomal degradation. May contribute to the innate restriction of retroviruses. Upon overexpression, reduces HIV-1 and murine leukemia virus infectivity, by suppressing viral gene expression. Antiviral activity depends on a functional E3 ubiquitin-protein ligase domain. May regulate TRIM5 turnover via the proteasome pathway, thus counteracting the TRIM5-mediated cross-species restriction of retroviral infection at early stages of the retroviral life cycle.
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分子量
- 52 kDa
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基因ID
- 81559
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UniProt
- Q96F44
抗原
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