TRIB3 抗体
Quick Overview for TRIB3 抗体 (ABIN7120255)
抗原
See all TRIB3 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- TRIB3 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- tribbles homolog 3(Drosophila)
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亚型
- IgG
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anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (AA 56-145) antibody
TRIB3 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3D7 unconjugated
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (AA 56-145) antibodyTRIB3 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 1H2 unconjugated
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (AA 152-325) antibodyTRIB3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (C-Term) antibodyTRIB3 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (AA 15-45), (N-Term) antibodyTRIB3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB4069-RB4070 unconjugated
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (AA 201-300) antibodyTRIB3 适用: 人, 大鼠 ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (Internal Region) antibodyTRIB3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (AA 1-358) antibodyTRIB3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (AA 1-358) antibodyTRIB3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (N-Term) antibodyTRIB3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:5000, IP: 1:200-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))
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别名
- TRIB3
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背景
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Synonyms: Tribbles homolog 3 (TRB-3)|Neuronal cell death-inducible putative kinase|SINK|p65-interacting inhibitor of NF-kappa-B|TRIB3|C20orf97|NIPK|SKIP3|TRB3
Background: Disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. May bind directly to and mask the 'Thr-308' phosphorylation site in AKT1. Binds to ATF4 and inhibits its transcriptional activation activity. Interacts with the NF-kappa-B transactivator p65 RELA and inhibits its phosphorylation and thus its transcriptional activation activity. Interacts with MAPK kinases and regulates activation of MAP kinases. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells. Does not display kinase activity. Inhibits the transcriptional activity of DDIT3/CHOP and is involved in DDIT3/CHOP-dependent cell death during ER stress. Can inhibit APOBEC3A editing of nuclear DNA.
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分子量
- 42 kDa
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基因ID
- 57761
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UniProt
- Q96RU7
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
抗原
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