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TNPO2 抗体

This anti-TNPO2 antibody is a 兔 多克隆 antibody detecting TNPO2 in WB, ELISA 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7120247
发货至: 中国

Quick Overview for TNPO2 抗体 (ABIN7120247)

抗原

See all TNPO2 抗体
TNPO2 (Transportin 2 (TNPO2))

适用

  • 12
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 9
  • 3

克隆类型

  • 10
  • 2
多克隆

标记

  • 12
This TNPO2 antibody is un-conjugated

应用范围

  • 12
  • 5
  • 5
  • 5
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    transportin 2

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IF: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    TNPO2 (Transportin 2 (TNPO2))

    别名

    TNPO2

    背景

    Synonyms: Background:Probably functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals(NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex(NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus(By similarity).

    分子量

    90-100 kDa

    基因ID

    30000

    UniProt

    O14787
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