TFB2M 抗体
Quick Overview for TFB2M 抗体 (ABIN7120070)
抗原
See all TFB2M 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- TFB2M antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- transcription factor B2, mitochondrial
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- TFB2M (Transcription Factor B2, Mitochondrial (TFB2M))
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别名
- TFB2M
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背景
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Synonyms: Dimethyladenosine transferase 2, mitochondrial|Hepatitis C virus NS5A-transactivated protein 5 (HCV NS5A-transactivated protein 5)|Mitochondrial 12S rRNA dimethylase 2|Mitochondrial transcription factor B2 (h-mtTFB, h-mtTFB2, hTFB2M, mtTFB2)|S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 2|TFB2M|NS5ATP5
Background: S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.
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分子量
- 45-50 kDa
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基因ID
- 64216
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UniProt
- Q9H5Q4
抗原
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