TRAIP 抗体
Quick Overview for TRAIP 抗体 (ABIN7120031)
抗原
See all TRAIP 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- TRAF interacting protein
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亚型
- IgG
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anti-TRAF Interacting Protein (TRAIP) (AA 67-313) antibody
TRAIP 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 3A4 unconjugated
anti-TRAF Interacting Protein (TRAIP) antibodyTRAIP 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-TRAF Interacting Protein (TRAIP) antibodyTRAIP 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-TRAF Interacting Protein (TRAIP) (AA 370-469) antibodyTRAIP 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-TRAF Interacting Protein (TRAIP) (C-Term) antibodyVerified TRAIP 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-TRAF Interacting Protein (TRAIP) (AA 370-469) antibodyTRAIP 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2E7 unconjugated
anti-TRAF Interacting Protein (TRAIP) (AA 328-356), (C-Term) antibodyTRAIP 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB17368 unconjugated
anti-TRAF Interacting Protein (TRAIP) (C-Term) antibodyTRAIP 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:10-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- TRAIP (TRAF Interacting Protein (TRAIP))
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别名
- TRAIP
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背景
- Synonyms:RNF206, TRIP Background:E3 ubiquitin ligase acting as a negative regulator of innate immune signaling. Inhibits activation of NF-kappa-B mediated by TNF. Negatively regulates TLR3/4-and RIG-I-mediated IRF3 activation and subsequent IFNB1 production and cellular antiviral response by promoting 'Lys-48'-linked polyubiquitination of TNK1 leading to its proteasomal degradation(By similarity)(PubMed:22945920). Involved in response to genotoxic lesions during genome replication. Promotes H2AX and RPA2 phosphorylation after replication-associated DNA damage and assists fork progression at UV-induced replication-blocking lesions during S phase(PubMed:26595769). Has also been proposed to play a role in promoting translesion synthesis by mediating the assembly of 'Lys-63'-linked poly-ubiquitin chains on the Y-family polymerase POLN in order to facilitate bypass of DNA lesions and preserve genomic integrity(PubMed:24553286). The function in translesion synthesis is controversial(PubMed:26595769).
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分子量
- 53 kDa
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基因ID
- 10293
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UniProt
- Q9BWF2
抗原
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