TRIAP1 抗体
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北京 101111
Quick Overview for TRIAP1 抗体 (ABIN7120027)
抗原
See all TRIAP1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- TRIAP1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- TP53 regulated inhibitor of apoptosis 1
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亚型
- IgG
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anti-TP53 Regulated Inhibitor of Apoptosis 1 (TRIAP1) (AA 1-76) antibody
TRIAP1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:5000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- TRIAP1 (TP53 Regulated Inhibitor of Apoptosis 1 (TRIAP1))
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别名
- TRIAP1
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背景
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Synonyms: TP53-regulated inhibitor of apoptosis 1|Protein 15E1.1|WF-1|p53-inducible cell-survival factor (p53CSV)|TRIAP1|15E1.1
Background: Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin(CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid(PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane(PubMed:23931759). Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid(PA) between liposomes(in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space(in vivo)(PubMed:26071602). Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis(PubMed:15735003).
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分子量
- 32 kDa
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基因ID
- 51499
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UniProt
- O43715
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途径
- Negative Regulation of intrinsic apoptotic Signaling
抗原
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