TNIP1 抗体
Quick Overview for TNIP1 抗体 (ABIN7119995)
抗原
See all TNIP1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- TNFAIP3 interacting protein 1
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亚型
- IgG
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anti-TNFAIP3 Interacting Protein 1 (TNIP1) antibody
TNIP1 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-TNFAIP3 Interacting Protein 1 (TNIP1) (AA 526-636) antibodyTNIP1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TNFAIP3 Interacting Protein 1 (TNIP1) antibodyTNIP1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-TNFAIP3 Interacting Protein 1 (TNIP1) (AA 1-636) antibodyTNIP1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-TNFAIP3 Interacting Protein 1 (TNIP1) (AA 99-148) antibodyTNIP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-TNFAIP3 Interacting Protein 1 (TNIP1) (N-Term) antibodyTNIP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-TNFAIP3 Interacting Protein 1 (TNIP1) (C-Term) antibodyTNIP1 适用: 人, 马, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-TNFAIP3 Interacting Protein 1 (TNIP1) (AA 454-482), (C-Term) antibodyTNIP1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB28148 unconjugated
anti-TNFAIP3 Interacting Protein 1 (TNIP1) (AA 454-482), (C-Term) antibodyTNIP1 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- TNIP1 (TNFAIP3 Interacting Protein 1 (TNIP1))
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别名
- TNIP1
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背景
- Synonyms:KIAA0113, NAF1 Background:Inhibits NF-kappa-B activation and TNF-induced NF-kappa-B-dependent gene expression by regulating A20/TNFAIP3-mediated deubiquitination of IKBKG, proposed to link A20/TNFAIP3 to ubiquitinated IKBKG. Involved in regulation of EGF-induced ERK1/ERK2 signaling pathway, blocks MAPK3/MAPK1 nuclear translocation and MAPK1-dependent transcription. Increases cell surface CD4(T4) antigen expression. Involved in the anti-inflammatory response of macrophages and positively regulates TLR-induced activation of CEBPB. Involved in the prevention of autoimmunity, this function implicates binding to polyubiquitin. Involved in leukocyte integrin activation during inflammation, this function is mediated by association with SELPLG and dependent on phosphorylation by SRC-family kinases. Interacts with HIV-1 matrix protein and is packaged into virions and overexpression can inhibit viral replication. May regulate matrix nuclear localization, both nuclear import of PIC(Preintegration complex) and export of GAG polyprotein and viral genomic RNA during virion production. In case of infection, promotes association of IKBKG with Shigella flexneri E3 ubiquitin-protein ligase ipah9.8 p which in turn promotes polyubiquitination of IKBKG leading to its proteasome-dependent degradation and thus is perturbing NF-kappa-B activation during bacterial infection.
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分子量
- 72 kDa
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基因ID
- 10318
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UniProt
- Q15025
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途径
- Activation of Innate immune Response
抗原
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