TRIP10 抗体
Quick Overview for TRIP10 抗体 (ABIN7119955)
抗原
See all TRIP10 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- TRIP10 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- thyroid hormone receptor interactor 10
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亚型
- IgG
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应用备注
- WB: 1:500-1:5000, IP: 1:500-1:5000, IF: 1:10-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- TRIP10 (Thyroid Hormone Receptor Interactor 10 (TRIP10))
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别名
- TRIP10
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背景
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Synonyms: Cdc42-interacting protein 4|Protein Felic|Salt tolerant protein (hSTP)|Thyroid receptor-interacting protein 10 (TR-interacting protein 10, TRIP-10)|TRIP10|CIP4|STOT|STP
Background: Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling(By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.
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分子量
- 75-85 kDa
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基因ID
- 9322
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UniProt
- Q15642
抗原
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