THOC6 抗体
Quick Overview for THOC6 抗体 (ABIN7119928)
抗原
See all THOC6 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- THOC6 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- THO complex 6 homolog(Drosophila)
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- THOC6 (THO Complex 6 Homolog (THOC6))
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别名
- THOC6
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背景
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Synonyms: THO complex subunit 6 homolog|Functional spliceosome-associated protein 35 (fSAP35)|WD repeat-containing protein 58|THOC6|WDR58
Background: Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex(EJC) and is recruited in a splicing-and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus(KSHV) intronless mRNAs and infectious virus production. Plays a role in apoptosis negative control involved in brain development.
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分子量
- 35 kDa
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基因ID
- 79228
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UniProt
- Q86W42
抗原
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