TXNDC5 抗体
Quick Overview for TXNDC5 抗体 (ABIN7119910)
抗原
See all TXNDC5 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- TXNDC5 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- thioredoxin domain containing 5 (endoplasmic reticulum)
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亚型
- IgG
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应用备注
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.1 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- TXNDC5 (Thioredoxin Domain Containing 5 (Endoplasmic Reticulum) (TXNDC5))
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别名
- TXNDC5
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背景
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Synonyms: Thioredoxin domain-containing protein 5|Endoplasmic reticulum resident protein 46 (ER protein 46, ERp46)|Thioredoxin-like protein p46|TXNDC5|TLP46
Background: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal endoplasmic reticulum (ER)-signal sequence, three catalytically active thioredoxin domains and a C-terminal ER-retention sequence. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S5 gene.
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分子量
- 50 kDa
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基因ID
- 81567
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UniProt
- Q8NBS9
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途径
- Cell RedoxHomeostasis
抗原
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