TEX14 抗体
Quick Overview for TEX14 抗体 (ABIN7119846)
抗原
See all TEX14 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- TEX14 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- testis expressed 14
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- TEX14 (Testis Expressed 14 (TEX14))
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别名
- TEX14
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背景
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Synonyms: Inactive serine/threonine-protein kinase TEX14|Protein kinase-like protein SgK307|Sugen kinase 307|Testis-expressed sequence 14|Testis-expressed sequence 14 protein|TEX14|SGK307
Background: Required both for the formation of intercellular bridges during meiosis and for kinetochore-microtubule attachment during mitosis. Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells and are required for spermatogenesis and male fertility. Acts by promoting the conversion of midbodies into intercellular bridges via its interaction with CEP55: interaction with CEP55 inhibits the interaction between CEP55 and PDCD6IP/ALIX and TSG101, blocking cell abscission and leading to transform midbodies into intercellular bridges. Also plays a role during mitosis: recruited to kinetochores by PLK1 during early mitosis and regulates the maturation of the outer kinetochores and microtubule attachment. Has no protein kinase activity in vitro(By similarity).
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分子量
- 180-200 kDa, 106 kDa
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基因ID
- 56155
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UniProt
- Q8IWB6
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途径
- Maintenance of Protein Location
抗原
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