电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

TEX14 抗体

This anti-TEX14 antibody is a 兔 多克隆 antibody detecting TEX14 in WB, ELISA, IHC 和 IP. Suitable for 人 和 小鼠.
产品编号 ABIN7119846
发货至: 中国

Quick Overview for TEX14 抗体 (ABIN7119846)

抗原

See all TEX14 抗体
TEX14 (Testis Expressed 14 (TEX14))

适用

  • 9
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
人, 小鼠

宿主

  • 8
  • 1

克隆类型

  • 8
  • 1
多克隆

标记

  • 9
This TEX14 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
  • 原理

    TEX14 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    testis expressed 14

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    TEX14 (Testis Expressed 14 (TEX14))

    别名

    TEX14

    背景

    Synonyms: Inactive serine/threonine-protein kinase TEX14|Protein kinase-like protein SgK307|Sugen kinase 307|Testis-expressed sequence 14|Testis-expressed sequence 14 protein|TEX14|SGK307

    Background: Required both for the formation of intercellular bridges during meiosis and for kinetochore-microtubule attachment during mitosis. Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells and are required for spermatogenesis and male fertility. Acts by promoting the conversion of midbodies into intercellular bridges via its interaction with CEP55: interaction with CEP55 inhibits the interaction between CEP55 and PDCD6IP/ALIX and TSG101, blocking cell abscission and leading to transform midbodies into intercellular bridges. Also plays a role during mitosis: recruited to kinetochores by PLK1 during early mitosis and regulates the maturation of the outer kinetochores and microtubule attachment. Has no protein kinase activity in vitro(By similarity).

    分子量

    180-200 kDa, 106 kDa

    基因ID

    56155

    UniProt

    Q8IWB6

    途径

    Maintenance of Protein Location
You are here:
Chat with us!