TELO2 抗体
Quick Overview for TELO2 抗体 (ABIN7119824)
抗原
See all TELO2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- TELO2 antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- TEL2, telomere maintenance 2, homolog
-
亚型
- IgG
-
-
anti-TEL2, Telomere Maintenance 2, Homolog (TELO2) (Internal Region) antibody
TELO2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-TEL2, Telomere Maintenance 2, Homolog (TELO2) (AA 786-812), (C-Term) antibodyTELO2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB24688 unconjugated
anti-TEL2, Telomere Maintenance 2, Homolog (TELO2) (AA 450-550) antibodyTELO2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000, IF: 1:20-1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- TELO2 (TEL2, Telomere Maintenance 2, Homolog (TELO2))
-
别名
- TELO2
-
背景
-
Synonyms: Telomere length regulation protein TEL2 homolog|Protein clk-2 homolog (hCLK2)|TELO2|KIAA0683
Background: Regulator of the DNA damage response(DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase(PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation(IR), ultraviolet(UV) and mitomycin C(MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals. May be involved in telomere length regulation.
-
分子量
- 92 kDa
-
基因ID
- 9894
-
UniProt
- Q9Y4R8
抗原
-
