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TEAD4 抗体

This anti-TEAD4 antibody is a 兔 多克隆 antibody detecting TEAD4 in WB, ELISA 和 IP. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7119813
发货至: 中国

Quick Overview for TEAD4 抗体 (ABIN7119813)

抗原

See all TEAD4 抗体
TEAD4 (TEA Domain Family Member 4 (TEAD4))

适用

  • 44
  • 24
  • 21
  • 6
  • 6
  • 6
  • 5
  • 5
  • 4
  • 3
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 39
  • 5

克隆类型

  • 40
  • 4
多克隆

标记

  • 26
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TEAD4 antibody is un-conjugated

应用范围

  • 41
  • 13
  • 12
  • 9
  • 6
  • 4
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunoprecipitation (IP)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    TEA domain family member 4

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IP: 1:200-1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    TEAD4 (TEA Domain Family Member 4 (TEAD4))

    别名

    TEAD4

    背景

    Synonyms:RTEF1, TCF13L1, TEF3 Background:Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition(EMT) induction. Binds specifically and non-cooperatively to the Sph and GT-IIC 'enhansons'(5'-GTGGAATGT-3') and activates transcription. Binds to the M-CAT motif.

    分子量

    65 kDa

    基因ID

    7004

    UniProt

    Q15561

    途径

    Regulation of Lipid Metabolism by PPARalpha
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