TEAD2 抗体
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北京 101111
Quick Overview for TEAD2 抗体 (ABIN7119811)
抗原
See all TEAD2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- TEAD2 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- TEA domain family member 2
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亚型
- IgG
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anti-TEA Domain Family Member 2 (TEAD2) (Internal Region) antibody
Verified TEAD2 适用: 人 ELISA, WB 宿主: 山羊 Polyclonal unconjugated
anti-TEA Domain Family Member 2 (TEAD2) antibodyTEAD2 适用: 人 ICC, DB 宿主: 小鼠 Monoclonal 404C5a unconjugated
anti-TEA Domain Family Member 2 (TEAD2) antibodyTEAD2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-TEA Domain Family Member 2 (TEAD2) (Internal Region) antibodyTEAD2 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TEA Domain Family Member 2 (TEAD2) antibodyTEAD2 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-TEA Domain Family Member 2 (TEAD2) (AA 218-307) antibodyTEAD2 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-TEA Domain Family Member 2 (TEAD2) (AA 40-120) antibodyTEAD2 适用: 人, 小鼠 ELISA, WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-TEA Domain Family Member 2 (TEAD2) (AA 1-447) antibodyTEAD2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-TEA Domain Family Member 2 (TEAD2) (N-Term) antibodyTEAD2 适用: 人, Cow, 犬, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-TEA Domain Family Member 2 (TEAD2) (AA 71-120) antibodyTEAD2 适用: 人, 小鼠 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- TEAD2 (TEA Domain Family Member 2 (TEAD2))
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别名
- TEAD2
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背景
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Synonyms: Transcriptional enhancer factor TEF-4|TEA domain family member 2 (TEAD-2)|TEAD2|TEF4
Background: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition(EMT) induction. Binds to the SPH and GT-IIC 'enhansons'(5'-GTGGAATGT-3'). May be involved in the gene regulation of neural development. Binds to the M-CAT motif.
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分子量
- 55-65 kDa
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基因ID
- 8463
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UniProt
- Q15562
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途径
- Regulation of Lipid Metabolism by PPARalpha, Tube Formation
抗原
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