TBC1D5 抗体
This anti-TBC1D5 antibody is a 兔 多克隆 antibody detecting TBC1D5 in WB, ELISA, IP 和 IHC. Suitable for 人, 小鼠 和 大鼠.
Quick Overview for TBC1D5 抗体 (ABIN7119805)
抗原
See all TBC1D5 抗体
TBC1D5
(TBC1 Domain Family, Member 5 (TBC1D5))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This TBC1D5 antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (IHC)
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- TBC1 domain family, member 5
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亚型
- IgG
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anti-TBC1 Domain Family, Member 5 (TBC1D5) (AA 446-795) antibody
TBC1D5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2400, IP: 1:200-1:1000 , IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- TBC1D5 (TBC1 Domain Family, Member 5 (TBC1D5))
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别名
- TBC1D5
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背景
- Synonyms:KIAA0210 Background:May act as a GTPase-activating protein(GAP) for Rab family protein(s). May act as a GAP for RAB7A. Can displace RAB7A and retromer CSC subcomplex from the endosomal membrane to the cytosol, at least retromer displacement seems to require its catalytic activity(PubMed:19531583, PubMed:20923837). Required for retrograde transport of cargo proteins from endosomes to the trans-Golgi network(TGN), the function seems to require its catalytic activity. Involved in regulation of autophagy(PubMed:22354992). May act as a molecular switch between endosomal and autophagosomal transport and is involved in reprogramming vesicle trafficking upon autophagy induction. Involved in the trafficking of ATG9A upon activation of autophagy. May regulate the recruitment of ATG9A-AP2-containing vesicles to autophagic membranes(PubMed:24603492).
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分子量
- 89 kDa
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基因ID
- 9779
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UniProt
- Q92609
抗原
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