TBC1D17 抗体 (AA 1-350)
Quick Overview for TBC1D17 抗体 (AA 1-350) (ABIN7119799)
抗原
See all TBC1D17 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-350
-
原理
- TBC1D17 antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
-
Immunogen sequence: 1-350aa
Immunogen: TBC1 domain family, member 17
-
亚型
- IgG
-
-
anti-TBC1 Domain Family, Member 17 (TBC1D17) (Middle Region) antibody
TBC1D17 适用: 人, 大鼠, 小鼠, Cow, 犬, 山羊, 豚鼠, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- TBC1D17 (TBC1 Domain Family, Member 17 (TBC1D17))
-
别名
- TBC1D17
-
背景
-
Synonyms: TBC1 domain family member 17|TBC1D17
Background: Probable GTPase-activating protein for Rab8, its transient association with Rab8 is mediated by OPTN. Inhibits Rab8-mediated endocytic trafficking, such as of transferrin receptor(TfR) and reduces Rab8 recruitnment to tubules emanating from the endocytic recycling compartment(ERC). Involved in regulation of autophagy. Mediates inhibition of autophagy caused by the OPTN variant GLC1E LYS-50, the function requires its catalytic activity, however, the involved Rab is not known.
-
分子量
- 73-100 kDa
-
基因ID
- 79735
-
UniProt
- Q9HA65
抗原
-
