DR1 抗体
Quick Overview for DR1 抗体 (ABIN7119791)
抗原
See all DR1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- DR1 antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- down-regulator of transcription 1, TBP-binding (negative cofactor 2)
-
亚型
- IgG
-
-
-
-
应用备注
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- DR1 (TATA-Binding Protein-Associated Phosphoprotein (DR1))
-
别名
- DR1
-
背景
-
Synonyms: Protein Dr1|Down-regulator of transcription 1|Negative cofactor 2-beta (NC2-beta)|TATA-binding protein-associated phosphoprotein|DR1
Background: This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription.
-
分子量
- 19 kDa
-
基因ID
- 1810
-
UniProt
- Q01658
抗原
-