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DR1 抗体

The 兔 多克隆 anti-DR1 antibody is suitable to detect DR1 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IHC, ELISA 和 IF.
产品编号 ABIN7119791
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for DR1 抗体 (ABIN7119791)

抗原

See all DR1 抗体
DR1 (TATA-Binding Protein-Associated Phosphoprotein (DR1))

适用

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人, 小鼠, 大鼠

宿主

  • 47
  • 2

克隆类型

  • 49
多克隆

标记

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This DR1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 原理

    DR1 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    down-regulator of transcription 1, TBP-binding (negative cofactor 2)

    亚型

    IgG
  • 应用备注

    WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    DR1 (TATA-Binding Protein-Associated Phosphoprotein (DR1))

    别名

    DR1

    背景

    Synonyms: Protein Dr1|Down-regulator of transcription 1|Negative cofactor 2-beta (NC2-beta)|TATA-binding protein-associated phosphoprotein|DR1

    Background: This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription.

    分子量

    19 kDa

    基因ID

    1810

    UniProt

    Q01658
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