TNKS 抗体
Quick Overview for TNKS 抗体 (ABIN7119769)
抗原
See all TNKS 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- TNKS antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
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亚型
- IgG
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anti-Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase (TNKS) (AA 35-130) antibody
TNKS 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase (TNKS) (AA 1017-1124) antibodyTNKS 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1A2 unconjugated
anti-Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase (TNKS) (Middle Region) antibodyTNKS 适用: 人, 小鼠, 大鼠, Cow, 兔, 马, 犬, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase (TNKS) (AA 972-1021) antibodyTNKS 适用: 人, Cow, 兔, Pig, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase (TNKS) (AA 1017-1124) antibodyTNKS 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A3 unconjugated
anti-Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase (TNKS) (AA 1050-1150) antibodyTNKS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase (TNKS) (N-Term) antibodyVerified TNKS 适用: 人 WB 宿主: 山羊 Polyclonal unconjugated
anti-Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase (TNKS) (AA 1079-1128) antibodyTNKS 适用: 人, 小鼠, 大鼠, Cow, 兔, 马, 犬, 豚鼠, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase (TNKS) (AA 448-497) antibodyTNKS 适用: 人, 小鼠, 大鼠, Cow, 兔, 马, 犬, 豚鼠, Pig, 斑马鱼, Bat, 猴, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase (TNKS) (Middle Region) antibodyTNKS 适用: 人, 小鼠, 大鼠, Cow, 兔, 马, 犬, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- TNKS (Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase (TNKS))
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别名
- TNKS
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背景
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Synonyms: Poly [ADP-ribose] polymerase tankyrase-1|ADP-ribosyltransferase diphtheria toxin-like 5 (ARTD5)|Poly [ADP-ribose] polymerase 5A|Protein poly-ADP-ribosyltransferase tankyrase-1|TNKS-1|TRF1-interacting ankyrin-related ADP-ribose polymerase|Tankyrase I|Tankyrase-1 (TANK1)|TNKS|PARP5A|PARPL|TIN1|TINF1|TNKS1
Background: Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation(PARsylation) of AXIN1 and AXIN2, 2 key components of the beta-catenin destruction complex: poly-ADP-ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation. Also mediates PARsylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subsequent ubiquitination. Mediates PARsylation of TERF1, thereby contributing to the regulation of telomere length. Involved in centrosome maturation during prometaphase by mediating PARsylation of HEPACAM2/MIKI. May also regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. May be involved in spindle pole assembly through PARsylation of NUMA1. Stimulates 26S proteasome activity.
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分子量
- 150 kDa
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基因ID
- 8658
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UniProt
- O95271
抗原
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