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SNCA 抗体

SNCA 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 5C6 unconjugated
产品编号 ABIN7119723
发货至: 中国
  • 抗原 See all SNCA 抗体
    SNCA (Synuclein, alpha (SNCA))
    适用
    • 291
    • 198
    • 198
    • 14
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    • 2
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    • 1
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    人, 大鼠, 小鼠
    宿主
    • 238
    • 96
    • 4
    • 1
    • 1
    • 1
    小鼠
    克隆类型
    • 223
    • 119
    单克隆
    标记
    • 143
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    This SNCA antibody is un-conjugated
    应用范围
    • 237
    • 164
    • 109
    • 80
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    • 68
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    • 52
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    • 44
    • 23
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    protein A+G purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    synuclein, alpha (non A4 component of amyloid precursor)
    克隆位点
    5C6
    亚型
    IgG1
    Top Product
    Discover our top product SNCA Primary Antibody
  • 应用备注
    WB: 1:500 - 1:2000, IHC: 1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    SNCA (Synuclein, alpha (SNCA))
    别名
    alpha-synuclein (SNCA 产品)
    别名
    snca antibody, MGC64356 antibody, LOC619283 antibody, NACP antibody, alphaSYN antibody, PARK1 antibody, PARK4 antibody, PD1 antibody, synuclein alpha L homeolog antibody, alpha-synuclein antibody, synuclein alpha antibody, synuclein, alpha antibody, snca.L antibody, LOC619283 antibody, SNCA antibody, Snca antibody
    背景
    Synonyms:Alpha synuclein, NACP, PARK1, PARK4, SNCA Background:Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.
    分子量
    18 kDa
    基因ID
    6622
    UniProt
    P37840
    途径
    Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
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