PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
有效期
12 months
抗原
SSX2IP
(Synovial Sarcoma, X Breakpoint 2 Interacting Protein (SSX2IP))
别名
SSX2IP
背景
Synonyms:KIAA0923 Background:Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions(AJs). May connect the nectin-afadin and E-cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin(By similarity). Involved in cell movement: localizes at the leading edge of moving cells in response to PDGF and is required for the formation of the leading edge and the promotion of cell movement, possibly via activation of Rac signaling(By similarity). Acts as a centrosome maturation factor, probably by maintaining the integrity of the pericentriolar material and proper microtubule nucleation at mitotic spindle poles. The function seems to implicate at least in part WRAP73, the SSX2IP:WRAP73 complex is proposed to act as regulator of spindle anchoring at the mitotic centrosome(PubMed:23816619, PubMed:26545777). Involved in ciliogenesis(PubMed:24356449). It is required for targeted recruitment of the BBSome, CEP290, RAB8, and SSTR3 to the cilia(PubMed:24356449).