SSX2IP 抗体
Quick Overview for SSX2IP 抗体 (ABIN7119696)
抗原
See all SSX2IP 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- SSX2IP antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- synovial sarcoma, X breakpoint 2 interacting protein
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- SSX2IP (Synovial Sarcoma, X Breakpoint 2 Interacting Protein (SSX2IP))
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别名
- SSX2IP
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背景
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Synonyms: Afadin- and alpha-actinin-binding protein (ADIP)|Afadin DIL domain-interacting protein|SSX2-interacting protein|SSX2IP|KIAA0923
Background: Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions(AJs). May connect the nectin-afadin and E-cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin(By similarity). Involved in cell movement: localizes at the leading edge of moving cells in response to PDGF and is required for the formation of the leading edge and the promotion of cell movement, possibly via activation of Rac signaling(By similarity). Acts as a centrosome maturation factor, probably by maintaining the integrity of the pericentriolar material and proper microtubule nucleation at mitotic spindle poles. The function seems to implicate at least in part WRAP73, the SSX2IP:WRAP73 complex is proposed to act as regulator of spindle anchoring at the mitotic centrosome(PubMed:23816619, PubMed:26545777). Involved in ciliogenesis(PubMed:24356449). It is required for targeted recruitment of the BBSome, CEP290, RAB8, and SSTR3 to the cilia(PubMed:24356449).
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分子量
- 64 kDa
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基因ID
- 117178
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UniProt
- Q9Y2D8
抗原
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