SS18L1 抗体
Quick Overview for SS18L1 抗体 (ABIN7119693)
抗原
See all SS18L1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Protein A+G purification
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- synovial sarcoma translocation gene on chromosome 18-like 1
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亚型
- IgG1
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anti-Synovial Sarcoma Translocation Gene On Chromosome 18-Like 1 (SS18L1) (AA 47-396) antibody
SS18L1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Synovial Sarcoma Translocation Gene On Chromosome 18-Like 1 (SS18L1) (AA 251-300) antibodySS18L1 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Synovial Sarcoma Translocation Gene On Chromosome 18-Like 1 (SS18L1) (AA 90-270) antibodySS18L1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Synovial Sarcoma Translocation Gene On Chromosome 18-Like 1 (SS18L1) (Middle Region) antibodySS18L1 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Cow, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000-1:6000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- SS18L1 (Synovial Sarcoma Translocation Gene On Chromosome 18-Like 1 (SS18L1))
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别名
- CREST
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背景
- Synonyms:CREST, KIAA0693, LP2261, SS18 like protein 1, SS18L1, SYT homolog 1 Background:Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein(CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP(By similarity).
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分子量
- 50 kDa
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UniProt
- O75177
抗原
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