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SYT1 抗体

This anti-SYT1 antibody is a 兔 多克隆 antibody detecting SYT1 in WB, IHC, ELISA 和 IP. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7119670
发货至: 中国

Quick Overview for SYT1 抗体 (ABIN7119670)

抗原

See all SYT1 抗体
SYT1 (Synaptotagmin I (SYT1))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This SYT1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    synaptotagmin I

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:1000, IP: 1:500-1:1000, IHC: 1:20-1:200, IF: 1:50-1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    SYT1 (Synaptotagmin I (SYT1))

    别名

    Synaptotagmin-1

    背景

    Synonyms:DKFZp781D2042, P65, SVP65, Synaptotagmin 1, synaptotagmin I, SYT, SYT1, SytI Background:The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis(PMID: 8058779). SYT1(synaptotagmin I) was firstly identified as a 65- kDa protein with a wide distribution in neuronal and neurosecretory tissue(PMID: 7298720). Calcium binding to SYT1 participates in triggering neurotransmitter release at the synapse(PMID: 11242035). In addition to regulating exocytosis, SYT1 has also been implicated in endocytosis and neurite outgrowth(PMID: 15492212, 11078930, 10336114). This antibody recognizes endogenous SYT1, which has an experimentally determined molecular mass of 65-68 kDa. An additional band of 47 kDa could also be detected, which is corresponding to the calculated molecular weight of SYT1.

    分子量

    65 kDa

    UniProt

    P21579

    途径

    Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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