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SYT1 抗体

This 兔 多克隆 anti-SYT1 antibody specifically detects SYT1 in WB, IHC, ELISA 和 IP. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN7119670
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SYT1 抗体 (ABIN7119670)

抗原

See all SYT1 抗体
SYT1 (Synaptotagmin I (SYT1))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

  • 98
  • 25
多克隆

标记

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This SYT1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
  • 原理

    SYT1 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    synaptotagmin I

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:1000, IP: 1:500-1:1000, IHC: 1:20-1:200, IF: 1:50-1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    SYT1 (Synaptotagmin I (SYT1))

    别名

    SYT1

    背景

    Synonyms: Synaptotagmin-1|Synaptotagmin I (SytI)|p65|SYT1|SVP65|SYT

    Background: The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis(PMID: 8058779). SYT1(synaptotagmin I) was firstly identified as a 65- kDa protein with a wide distribution in neuronal and neurosecretory tissue(PMID: 7298720). Calcium binding to SYT1 participates in triggering neurotransmitter release at the synapse(PMID: 11242035). In addition to regulating exocytosis, SYT1 has also been implicated in endocytosis and neurite outgrowth(PMID: 15492212, 11078930, 10336114). This antibody recognizes endogenous SYT1, which has an experimentally determined molecular mass of 65-68 kDa. An additional band of 47 kDa could also be detected, which is corresponding to the calculated molecular weight of SYT1.

    分子量

    65 kDa

    UniProt

    P21579

    途径

    Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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