SUV39H2 抗体
Quick Overview for SUV39H2 抗体 (ABIN7119617)
抗原
See all SUV39H2 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- suppressor of variegation 3-9 homolog 2(Drosophila)
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亚型
- IgG
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anti-Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) antibody
SUV39H2 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) (AA 360-390) antibodySUV39H2 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) (AA 93-122) antibodySUV39H2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) (AA 201-410) antibodySUV39H2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) (AA 93-122), (N-Term) antibodySUV39H2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB02737 unconjugated
anti-Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) (Internal Region) antibodySUV39H2 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) (Internal Region) antibodySUV39H2 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) (AA 141-350) antibodySUV39H2 适用: 人 WB, ChIP, IF 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) (AA 360-390), (C-Term) antibodySUV39H2 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB02739 unconjugated
anti-Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) antibodySUV39H2 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- SUV39H2 (Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2))
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别名
- SUV39H2
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背景
- Synonyms:KMT1B Background:Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1(CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats. SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes, such as cell cycle regulation, transcriptional repression and regulation of telomere length. May participate in regulation of higher-order chromatin organization during spermatogenesis. Recruited by the large PER complex to the E-box elements of the circadian target genes such as PER2 itself or PER1, contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 'Lys-9' trimethylation.
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分子量
- 53 kDa
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基因ID
- 79723
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UniProt
- Q9H5I1
抗原
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