SUPV3L1 抗体
Quick Overview for SUPV3L1 抗体 (ABIN7119615)
抗原
See all SUPV3L1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- SUPV3L1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- suppressor of var1, 3-like 1
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- SUPV3L1 (Suppressor of Var1, 3-Like 1 (SUPV3L1))
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别名
- SUPV3L1
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背景
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Synonyms: ATP-dependent RNA helicase SUPV3L1, mitochondrial|Suppressor of var1 3-like protein 1 (SUV3-like protein 1)|SUPV3L1|SUV3
Background: Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome(mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded(ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria, regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA.
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分子量
- 70-80 kDa
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UniProt
- Q8IYB8
抗原
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