STT3A 抗体
Quick Overview for STT3A 抗体 (ABIN7119563)
抗原
See all STT3A 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- STT3A antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- STT3, subunit of the oligosaccharyltransferase complex, homolog A
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亚型
- IgG
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应用备注
- WB: 1:1000-1:5000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- STT3A (STT3, Subunit of The Oligosaccharyltransferase Complex, Homolog A (STT3A))
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别名
- STT3A
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背景
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Synonyms: Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (Oligosaccharyl transferase subunit STT3A, STT3-A)|B5|Integral membrane protein 1|Transmembrane protein TMC|STT3A|ITM1|TMC
Background: Catalytic subunit of the N-oligosaccharyl transferase(OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum(ER). SST3A seems to be involved in complex substrate specificity. STT3A is present in the majority of OST complexes and mediates cotranslational N-glycosylation of most sites on target proteins, while STT3B-containing complexes are required for efficient cotranslational glycosylation and mediate glycosylation of sites that have been skipped by STT3A.
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分子量
- 100 kDa
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基因ID
- 3703
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UniProt
- P46977
抗原
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