STEAP3 抗体
Quick Overview for STEAP3 抗体 (ABIN7119514)
抗原
See all STEAP3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- STEAP3 antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- STEAP family member 3
-
亚型
- IgG
-
-
-
-
应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))
-
别名
- STEAP3
-
背景
-
Synonyms: Metalloreductase STEAP3|Dudulin-2|Six-transmembrane epithelial antigen of prostate 3|Tumor suppressor-activated pathway protein 6 (hTSAP6)| pH yde (h pH yde)|STEAP3|TSAP6
Background: Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NADP(+) as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.
-
分子量
- 55 kDa
-
基因ID
- 55240
-
UniProt
- Q658P3
-
途径
- Transition Metal Ion Homeostasis
抗原
-