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SOX2 抗体 (AA 129-317)

This anti-SOX2 antibody is a 兔 多克隆 antibody detecting SOX2 in WB, ELISA, IHC 和 IF. Suitable for 人, 小鼠, 大鼠 和 斑马鱼.
产品编号 ABIN7119471
发货至: 中国

Quick Overview for SOX2 抗体 (AA 129-317) (ABIN7119471)

抗原

See all SOX2 抗体
SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

适用

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人, 小鼠, 大鼠, 斑马鱼

宿主

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  • 2

克隆类型

  • 159
  • 67
多克隆

标记

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This SOX2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 129-317

    原理

    SOX2 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Immunogen sequence: 129-317aa

    Immunogen: SRY(sex determining region Y)-box 2

    亚型

    IgG
  • 应用备注

    WB: 1:2000-1:20000, IHC: 1:50-1:200, IF: 1:50-1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

    别名

    SOX2

    背景

    Synonyms: Transcription factor SOX-2|SOX2

    Background: Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206(By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal(By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation(By similarity).

    分子量

    34 kDa

    基因ID

    6657

    UniProt

    P48431

    途径

    Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
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