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SKAP2 抗体

This anti-SKAP2 antibody is a 兔 多克隆 antibody detecting SKAP2 in WB, ELISA, IHC 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7119461
发货至: 中国

Quick Overview for SKAP2 抗体 (ABIN7119461)

抗原

See all SKAP2 抗体
SKAP2 (Src Kinase Associated Phosphoprotein 2 (SKAP2))

适用

  • 38
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  • 1
人, 小鼠, 大鼠

宿主

  • 35
  • 2
  • 1

克隆类型

  • 38
多克隆

标记

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  • 1
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This SKAP2 antibody is un-conjugated

应用范围

  • 36
  • 17
  • 13
  • 13
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  • 5
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  • 1
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 原理

    SKAP2 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    src kinase associated phosphoprotein 2

    亚型

    IgG
  • 应用备注

    WB: 1:500 - 1:2000, IHC: 1:50 - 1:100, IF: 1:50 - 1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    SKAP2 (Src Kinase Associated Phosphoprotein 2 (SKAP2))

    别名

    SKAP2

    背景

    Synonyms: Src kinase-associated phosphoprotein 2|Pyk2/RAFTK-associated protein|Retinoic acid-induced protein 70|SKAP55 homolog (SKAP-55HOM, SKAP-HOM)|Src family-associated phosphoprotein 2|Src kinase-associated phosphoprotein 55-related protein|Src-associated adapter protein with PH and SH3 domains|SKAP2|PRAP|RA70|SAPS|SCAP2|SKAP55R

    Background: The protein encoded by this gene shares homology with Src kinase-associated phosphoprotein 1, and is a substrate of Src family kinases. It is an adaptor protein that is thought to play an essential role in the Src signaling pathway, and in regulating proper activation of the immune system. This protein contains an amino terminal coiled-coil domain for self-dimerization, a plecskstrin homology (PH) domain required for interactions with lipids at the membrane, and a Src homology (SH3) domain at the carboxy terminus. Some reports indicate that this protein inhibits actin polymerization through interactions with actin assembly factors, and might negatively regulate the invasiveness of tumors by modulating actin assembly. Alternative splicing results in multiple transcript variants encoding different isoforms.

    分子量

    50 kDa

    基因ID

    8935

    UniProt

    O75563
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