SQLE 抗体
Quick Overview for SQLE 抗体 (ABIN7119452)
抗原
See all SQLE 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- squalene epoxidase
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亚型
- IgG
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应用备注
- WB: 1:200-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- SQLE (Squalene Epoxidase (SQLE))
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别名
- SQLE
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背景
- Synonyms:ERG1, FLJ30795, SE, SM, SQLE, squalene epoxidase, Squalene monooxygenase Background:SQLE, also named as ERG1, SE and SM, belongs to the squalene monooxygenase family. It catalyzes the first oxygenation step in cholesterol synthesis, acting on squalene before cyclization into the basic steroid structure. SQLE may serve as a flux-controlling enzyme beyond 3-hydroxy-3-methylglutaryl-coenzyme A reductase(HMGR, considered as rate limiting). It is also posttranslationally regulated by cholesterol-dependent proteasomal degradation.(PMID:21356516) The MW of SQLE is about 64kd.
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分子量
- 64 kDa
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基因ID
- 6713
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UniProt
- Q14534
抗原
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