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SFPQ 抗体

This anti-SFPQ antibody is a 兔 多克隆 antibody detecting SFPQ in WB, IHC 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7119440
发货至: 中国

Quick Overview for SFPQ 抗体 (ABIN7119440)

抗原

See all SFPQ 抗体
SFPQ (Splicing Factor Proline/glutamine-Ric (SFPQ))

适用

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  • 2
  • 1
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人, 小鼠, 大鼠

宿主

  • 44
  • 2

克隆类型

  • 34
  • 12
多克隆

标记

  • 30
  • 3
  • 3
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  • 1
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This SFPQ antibody is un-conjugated

应用范围

  • 33
  • 16
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  • 1
  • 1
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated)

    亚型

    IgG
  • 应用备注

    WB: 1:500 - 1:1000, IHC: 1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3 ,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    SFPQ (Splicing Factor Proline/glutamine-Ric (SFPQ))

    别名

    SFPQ

    背景

    Synonyms:PSF Background:SFPQ, also named PSF, encodes a nuclear factor implicated in the splicing and regulation of gene expression. SFPQ probably forms a heteromer with NONO and participates in DNA pairing and DNA break repair program. Very recently SFPQ was identified as a downstream target of tau, complete nuclear depletion and cytoplasmic accumulation of SFPQ were shown in the neurons and astrocytes of brains with Alzheimer's disease (AD), more strikingly, reduced SFPQ levels may progress together with tau pathology, these observation strongly suggests the important role of SFPQ pathology in neurodegenerative diseases including AD. SFPQ protein may appears as 47 kDa, 52 kDa or 100 kDa molecules in various cell types. This antibody is a rabbit polyclonal antibody raised against the N-terminal of human SFPQ.

    分子量

    115 kDa

    基因ID

    6421

    UniProt

    P23246
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