SFPQ 抗体
Quick Overview for SFPQ 抗体 (ABIN7119440)
抗原
See all SFPQ 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- SFPQ antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated)
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亚型
- IgG
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anti-Splicing Factor Proline/glutamine-Ric (SFPQ) (AA 269-361) antibody
SFPQ 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 6D7 unconjugated
anti-Splicing Factor Proline/glutamine-Ric (SFPQ) (AA 578-707) antibodySFPQ 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor Proline/glutamine-Ric (SFPQ) antibodySFPQ 适用: 人 IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Splicing Factor Proline/glutamine-Ric (SFPQ) antibodySFPQ 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor Proline/glutamine-Ric (SFPQ) (N-Term) antibodySFPQ 适用: 人, 小鼠, 大鼠, Cow, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor Proline/glutamine-Ric (SFPQ) (C-Term) antibodySFPQ 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor Proline/glutamine-Ric (SFPQ) (AA 191-240) antibodySFPQ 适用: 人, 小鼠, 大鼠, Cow, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor Proline/glutamine-Ric (SFPQ) (AA 269-362) antibodySFPQ 适用: 人 WB, IHC, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 6D7 unconjugated
anti-Splicing Factor Proline/glutamine-Ric (SFPQ) (AA 444-493) antibodySFPQ 适用: 人, 小鼠, 大鼠, Cow, 小鸡, 马, 豚鼠, 兔, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor Proline/glutamine-Ric (SFPQ) (Middle Region) antibodySFPQ 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500 - 1:1000, IHC: 1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- SFPQ (Splicing Factor Proline/glutamine-Ric (SFPQ))
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别名
- SFPQ
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背景
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Synonyms: Splicing factor, proline- and glutamine-rich|100 kDa DNA-pairing protein (hPOMp100)|DNA-binding p52/p100 complex, 100 kDa subunit|Polypyrimidine tract-binding protein-associated-splicing factor (PSF, PTB-associated-splicing factor)|SFPQ|PSF
Background: SFPQ, also named PSF, encodes a nuclear factor implicated in the splicing and regulation of gene expression. SFPQ probably forms a heteromer with NONO and participates in DNA pairing and DNA break repair program. Very recently SFPQ was identified as a downstream target of tau, complete nuclear depletion and cytoplasmic accumulation of SFPQ were shown in the neurons and astrocytes of brains with Alzheimer's disease (AD), more strikingly, reduced SFPQ levels may progress together with tau pathology, these observation strongly suggests the important role of SFPQ pathology in neurodegenerative diseases including AD. SFPQ protein may appears as 47 kDa, 52 kDa or 100 kDa molecules in various cell types. This antibody is a rabbit polyclonal antibody raised against the N-terminal of human SFPQ.
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分子量
- 115 kDa
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基因ID
- 6421
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UniProt
- P23246
抗原
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