SF3B2 抗体
Quick Overview for SF3B2 抗体 (ABIN7119435)
抗原
See all SF3B2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- SF3B2 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- splicing factor 3b, subunit 2, 145kDa
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亚型
- IgG
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应用备注
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- SF3B2 (Splicing Factor 3b, Subunit 2, 145kDa (SF3B2))
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别名
- SF3B2
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背景
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Synonyms: Splicing factor 3B subunit 2|Pre-mRNA-splicing factor SF3b 145 kDa subunit (SF3b145)|Spliceosome-associated protein 145 (SAP 145)|SF3B2|SAP145
Background: This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus.
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分子量
- 140 kDa
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基因ID
- 10992
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UniProt
- Q13435
抗原
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