SPATA13 抗体
Quick Overview for SPATA13 抗体 (ABIN7119403)
抗原
See all SPATA13 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- SPATA13 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- spermatogenesis associated 13
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亚型
- IgG
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anti-Spermatogenesis Associated 13 (SPATA13) antibody
SPATA13 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Spermatogenesis Associated 13 (SPATA13) (AA 204-232) antibodySPATA13 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB27015 unconjugated
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应用备注
- WB: 1:500-1:2000, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- SPATA13 (Spermatogenesis Associated 13 (SPATA13))
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别名
- SPATA13
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背景
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Synonyms: Spermatogenesis-associated protein 13|APC-stimulated guanine nucleotide exchange factor 2 (Asef2)|SPATA13
Background: Acts as guanine nucleotide exchange factor(GEF) for RHOA, RAC1 and CDC42 GTPases. Regulates cell migration and adhesion assembly and disassembly through a RAC1, PI3K, RHOA and AKT1-dependent mechanism. Increases both RAC1 and CDC42 activity, but decreases the amount of active RHOA. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.
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分子量
- 75 kDa
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基因ID
- 221178
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UniProt
- Q96N96
抗原
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