SNX5 抗体
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北京 101111
Quick Overview for SNX5 抗体 (ABIN7119364)
抗原
See all SNX5 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- SNX5 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- sorting nexin 5
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亚型
- IgG
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anti-Sorting Nexin 5 (SNX5) (AA 7-245) antibody
SNX5 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sorting Nexin 5 (SNX5) antibodyKD Validated SNX5 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB2310 unconjugated Recombinant Antibody
anti-Sorting Nexin 5 (SNX5) antibodySNX5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sorting Nexin 5 (SNX5) (C-Term) antibodyVerified SNX5 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Sorting Nexin 5 (SNX5) (AA 145-404) antibodySNX5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sorting Nexin 5 (SNX5) (C-Term) antibody (Biotin)Verified SNX5 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal Biotin
anti-Sorting Nexin 5 (SNX5) (AA 72-121) antibodySNX5 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 马, 兔, 斑马鱼, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Sorting Nexin 5 (SNX5) (AA 31-80) antibodySNX5 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 马, 兔, 斑马鱼, 豚鼠, 猴, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Sorting Nexin 5 (SNX5) antibodySNX5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sorting Nexin 5 (SNX5) (N-Term) antibodySNX5 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- SNX5 (Sorting Nexin 5 (SNX5))
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别名
- SNX5
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背景
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Synonyms: Sorting nexin-5|SNX5
Background: Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate(PtdIns(3P)) or phosphatidylinositol 3,4-bisphosphate(PtdIns(3,4)P2)(PubMed:15561769). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network(TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier(ETC)(Probable). Does not have in vitro vesicle-to-membrane remodeling activity(PubMed:23085988). Involved in retrograde transport of lysosomal enzyme receptor IGF2R(PubMed:17148574, PubMed:18596235). May function as link between endosomal transport vesicles and dynactin(Probable). Plays a role in the internalization of EGFR after EGF stimulation(Probable). Involved in EGFR endosomal sorting and degradation, the function involves PIP5K1C isoform 3 and is retromer-independent(PubMed:23602387). Together with PIP5K1C isoform 3 facilitates HGS interaction with ubiquitinated EGFR, which initiates EGFR sorting to intraluminal vesicles(ILVs) of the multivesicular body for subsequent lysosomal degradation(Probable). Involved in E-cadherin sorting and degradation, inhibits PIP5K1C isoform 3-mediated E-cadherin degradation(PubMed:24610942). Plays a role in macropinocytosis(PubMed:18854019, PubMed:21048941).
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分子量
- 47 kDa
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基因ID
- 27131
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UniProt
- Q9Y5X3
抗原
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